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Pomegranat Complex kapsler mod ultraviolette stråler
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 Granatæbleekstrakt beskytter mod virkningen af ultraviolette B-stråler ved at hæmme ultraviolet, lysstimuleret NFkB-aktivering. Ekstraktet var også i stand til at forebygge kemisk fremkaldt hudkræft hos mus ved at påvirke kræftens opståen og udvikling ved hjælp af NFkB.
Blokering af NFkB ved hjælp af Pomegranat Complex granatæbleekstrakt har også vist sig at kunne lindre slidgigt ved at hæmme produktionen af proteinfordøjende enzymer og inflammatoriske cytokiner.
Referencer:
Afaq F, Malik A, Syed D, et al. Pomegranate fruit extract modulates UV-B-mediated phosphorylation of mitogen-activated protein kinases and activation of nuclear factor kappa B in normal human epidermal keratinocytes paragraph sign. Photochem Photobiol. Januar 2005;81(l):38-45.
Afaq F, Saleem M, Krueger CG, Reed JD, Mukhtar H. Anthocyanin- and hydrolyzable tannin-rich pomegranate fruit extract modulates MAPK and NF-kappaB pathways and inhibits skin tumorigenesisinCD-1 mice. Int J Cancer. 20. januar 2005;113(3):423-33.
Ahmed S, Wang N, Hafeez BB, Cheruvu VK, Haqqi TM. Punica granatum L. extract inhibits IL-1beta-induced expression of matrix metalloproteinases by inhibiting the activation of MAP kinases and NF- kappaB in human chondrocytes in vitro. J Nutr. September 2005;135(9):2096-102.
Schubert SY, Neeman I, Resnick N. A novel mechanism for the inhibition of NF-kappaB activation in vascular endothelial cells by natural antioxidants. FASEB J. December 2002;16(14):1931-3.
Tzima E, Irani-Tehrani M, Kiosses WB, et al. A mechanosensory complex that mediates the endothelial cell response to fluid shear stress. Nature. 15. september 2005;437(7057):426-31.
Health News 2011
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